Sensor-Based CRT OptimiSation Benefits Sicker Patients



The RESPOND-CRT study is a relevant and significant study in the field of cardiac resynchronization therapy. It has answered an important question finally, that optimization can work, and that optimization, if done on an individual basis, in an automatic fashion, repetitively, can actually translate into better outcomes. Not only was there a significant reduction in HF hospitalization for patients in the SonR arm, there were also significant benefits found for sicker patients, in particular those with a history of AF and renal failure. Jagmeet Singh (Boston, USA), Angelo Aurrichio (Lugano, Switzerland) and Josep Brugada (Barcelona, Spain) discuss the results of the sub-analysis conducted on patient subgroups and the implications for clinical practice.

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