Philips, in collaboration with Radcliffe Cardiology, are pleased to present an expert video case study filmed at the laboratory of Prof. Javier Escaned (Madrid, ES). Prof. Javier Escaned is Head of the Interventional Cardiology Section at Hospital Clinico San Carlos. His main interests in the field of interventional cardiology include intracoronary imaging and physiology, complex percutaneous coronary intervention including chronic total occlusion recanalisation, and acute coronary syndromes. In this video, Prof Escaned demonstrates in a practical setting the techniques and tools he employs to maximise outcomes for his patients with diffuse coronary artery disease. This recorded case features IVUS and iFR-guided PCI of a 71-year old male with diffuse coronary artery disease.