Persistent Ductus Arteriosus

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  • Patent ductus arteriosus (PDA), where the ductus arteriosus fails to close after birth, is rare in healthy term newborns. As gestational age decreases, the incidence of PDA increases. In extremely premature infants, especially those with respiratory distress syndrome, up to 80% may have a PDA at 3 days of age.

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    Patent ductus arteriosus (PDA), where the ductus arteriosus fails to close after birth, is rare in healthy term newborns. As gestational age decreases, the incidence of PDA increases. In extremely premature infants, especially those with respiratory distress syndrome, up to 80% may have a PDA at 3 days of age.

    In gestationally more mature infants, conservative management of a PDA may be sufficient to support the infant while awaiting spontaneous closure. Conservative management includes careful fluid restriction (110 to 130ml/kg/d while monitoring urine output) and increasing peak end-expiratory pressure (PEEP) to treat pulmonary oedema.

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