Takotsubo Cardiomyopathy

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  • Takotsubo cardiomyopathy (TCM) is a transient wall motion abnormality of the left ventricular (LV) apex accompanied with emotional or physical stress that usually resolves completely. It occurs more often in postmenopausal women. It is characterised by acute transient apical ballooning of the left ventricle in the absence of obstructive coronary artery disease.

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    Takotsubo cardiomyopathy (TCM) is a transient wall motion abnormality of the left ventricular (LV) apex accompanied with emotional or physical stress that usually resolves completely. It occurs more often in postmenopausal women. It is characterised by acute transient apical ballooning of the left ventricle in the absence of obstructive coronary artery disease.

    The transient myocardial dysfunction in Takotsubo cardiomyopathy appears to be mediated by myocardial oedema, which can be detected by a lengthened native T1 value in regions with oedema and dysfunction.

    Treatment of TCM during the acute phase is mainly symptomatic treatment. Intra-aortic balloon pump equipment is required for haemodynamically unstable patients in addition to cardiopulmonary circulatory support and continuous veno-venous haemofiltration. Levosimendan may be beneficial because of its inotropic action and vasodilator effect. Usage of anticoagulants may be considered at least until systolic function is recovered.

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