From the Department of Pharmacy and Therapeutics, School of Pharmacy (I.H.), Department of Health Policy and Management, Graduate School of Public Health (Y.Z.), and Department of Epidemiology, Graduate School of Public Health (M.M.B.), University of Pittsburgh, PA; Department of Medicine, University of Otago, Christchurch, New Zealand (P.K.L.C.); and Heart and Valvular Institute, University of Pittsburgh Medical Centre, PA (S.S.).