Prof Patrick Serruys is an expert in interventional cardiology, He and a colleague developed drug-eluting stents, which drastically reduced restenosis after procedures. He later devised a fully biodegradable drug-eluting scaffold so a permanent metallic stent would not need to be implanted in patients. He previously led on establishing the methodology of quantitative coronary angiography. Along with having an office “full of diplomas and medals”, he has won career achievement awards from TCT and the American College of Cardiology, as well as the gold medal of the European Society of Cardiology. He acknowledges that introducing something new has immense ethical issues and advises practitioners to remain curious and open to novelty.