Nicolas M Van Mieghem

Nicolas M Van Mieghem

Medical Director

PhD FESC

Thoraxcenter, Erasmus University Medical Center, Rotterdam, NL

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Biography

Prof Van Mieghem initially intended to train as a cardiac surgeon but decided to specialise in interventional cardiology instead, following advice from a mentor. This decision was cemented when he read the first-in-human case report of transcatheter aortic valve implantation (TAVI) in Circulation by Alain Cribier in 2002. Prof Van Mieghem believes that great cardiologist genuinely cares for their patients. He names Gary Roubin, Dr Manu Malbrain and Professor Patrick Serruys among his mentors. 

 

His current research focuses on cerebral embolic protection during TAVI and the search for improved large bore closure devices. He works actively in expanding TAVI indications, most notably TAVI as a means to further unload the left ventricle in heart failure patients with moderate aortic stenosis (the TAVR UNLOAD trial). Prof Van Mieghem is also involved in the development and dispersion of mechanical circulatory support (MCS) devices as well as transcatheter mitral and tricuspid repair techniques. In terms of imaging and preprocedural planning, his research has covered computed tomography (CT)-derived 3D modelling and printing.

 

As well as his involvement in percutaneous coronary interventions and structural heart programs, he has published and co-authored over 350 scientific papers in peer-reviewed journals. Professor Van Mieghem is a principal investigator and steering committee member in multiple ongoing international trials, evaluating various coronary and transcatheter valve technologies. He is a Fellow of the European Society of Cardiology (FESC) 

 

 Prof Van Mieghem is on the ICR3 Editorial Board.

 

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Media

NVM Cardiology Meeting Reflections: AHA 25 Preview

Nicolas M Van Mieghem

Watch time: 9m 56s
NVM Cardiology Meeting Reflections: What's Hot at TCT 25?

Nicolas M Van Mieghem

Watch time: 14m 58s
Expanding TAVI to Low- And Intermediate-Risk Patients

Nicolas M Van Mieghem, Joanna J Wykrzykowska, Giuseppe Tarantini, et al

Watch time: 27m 1s
View from the Thoraxcenter: ESC 25 Late-breaking Science Wrap-Up

Nicolas M Van Mieghem, Joost Daemen

Watch time: 47m 54s

Nicolas M Van Mieghem, Joost Daemen

Watch time: 13m 42s
View from the Thoraxcenter: ESC 2025 Interventional Cardiology Preview

Nicolas M Van Mieghem, Joost Daemen

Watch time: 20m 32s

Nicolas M Van Mieghem

Watch time: 11m 48s (2 videos)
View from the Thoraxcenter: ESC Congress 25 Preview

Joost Daemen, Nicolas M Van Mieghem

Watch time: 36m 33s

Joost Daemen, Nicolas M Van Mieghem

Watch time: 5h 48m 39s (30 videos)
View from the Thoraxcenter: EuroPCR 25 Wrap Up

Joost Daemen, Nicolas M Van Mieghem

Watch time: 43m 36s

Joost Daemen, Nicolas M Van Mieghem

Watch time: 2h 27m 56s (15 videos)
View from the Thoraxcenter: EuroPCR 25 Late-breaking Preview

Joost Daemen, Nicolas M Van Mieghem

Watch time: 26m 38s
View from the Thoraxcenter: ACC 25 Wrap Up

Joost Daemen, Nicolas M Van Mieghem

Watch time: 39m 2s
View from the Thoraxcenter: What's Hot at ACC.25?

Joost Daemen, Nicolas M Van Mieghem

Watch time: 30m 45s
View from the Thoraxcenter: AHA 24 Wrap-Up

Joost Daemen, Nicolas M Van Mieghem

Watch time: 17m 38s
TCT 24 Late-breaking Science Wrap Up

Joost Daemen, Nicolas M Van Mieghem

Watch time: 48m 41s
TCT 24: The TAVR UNLOAD Trial

Nicolas M Van Mieghem

Watch time: 4m 10s

Joost Daemen, Nicolas M Van Mieghem

View from the Thoraxcenter: What's Hot at AHA 24?

Joost Daemen, Nicolas M Van Mieghem

Watch time: 13m 43s
View from the Thoraxcenter: What's Hot at TCT 24?

Nicolas M Van Mieghem, Joost Daemen

Watch time: 38m 7s
View from the Thoraxcenter: ESC 24 Hot Line Science Wrap Up

Nicolas M Van Mieghem, Joost Daemen

Watch time: 47m 31s

Broadcast

Intervention
Transcatheter Interventions Online 2025 - Day Four

Ajay J Kirtane, Azeem Latib, Eric Secemsky, et al

Broadcast

Intervention
Transcatheter Interventions Online 2025 - Day Three

Nicolas M Van Mieghem, David Hildick-Smith, Roxana Mehran, et al

Broadcast

Intervention
Transcatheter Interventions Online 2025 - Day Two

Nicolas M Van Mieghem, David Hildick-Smith, Roxana Mehran, et al

Broadcast

Intervention
Transcatheter Interventions Online 2025 - Day One

Nicolas M Van Mieghem, David Hildick-Smith, Roxana Mehran, et al

View from the Thoraxcenter: ESC Congress 24 Hot Line Preview

Nicolas M Van Mieghem, Joost Daemen

Watch time: 27m 27s
View from the Thoraxcenter: EuroPCR 24 Wrap Up - Part 1

Nicolas M Van Mieghem, Joost Daemen

Watch time: 18m 29s
View from the Thoraxcenter: What's Hot at EuroPCR 24?

Nicolas M Van Mieghem, Joost Daemen

Watch time: 26m 3s
View from the Thoraxcenter: ACC.24 Late-breaking Science Wrap Up

Nicolas M Van Mieghem, Joost Daemen

Watch time: 43m 48s
Exploring the Potential of Sensor-Guided TAVI

Nicolas M Van Mieghem, Danny Dvir, Ander Regueiro, et al

View from the Thoraxcenter: What's Hot at ACC.24?

Nicolas M Van Mieghem, Joost Daemen

Watch time: 28m 9s

Nicolas M Van Mieghem, Ajay J Kirtane, Holger Thiele, et al

Broadcast

Imaging & Diagnostics

Intervention
iPCI Meeting 2024 - Day 1

Joost Daemen, Gijs van Soest, Kalaivani Mahadevan, et al

Nicolas M Van Mieghem, Federico Pappalardo, Divaka Perera, et al

Watch time: 1s (2 videos)

Nicolas M Van Mieghem, Giuseppe Tarantini, Alaide Chieffo, et al

Watch time: 50m (5 videos)
View from the Thoraxcenter: AHA 23 Late-breaking Science Wrap Up

Nicolas M Van Mieghem, Joost Daemen

Watch time: 23m 13s
View from the Thoraxcenter: AHA 23 Wrap Up

Nicolas M Van Mieghem, Joost Daemen,

Listen time: 23m 14s
View from the Thoraxcenter: AHA 23 Wrap Up

Nicolas M Van Mieghem,

Listen time: 23m 14s
View from the Thoraxcenter: AHA 23 Late-breaking Science Preview

Nicolas M Van Mieghem, Joost Daemen

Watch time: 12m 34s
View from the Thoraxcenter: TCT 23 Late-breaking Science Wrap Up

Nicolas M Van Mieghem, Joost Daemen

Watch time: 30m 36s
View from the Thoraxcenter: TCT 23 Wrap Up

Nicolas M Van Mieghem, Joost Daemen,

Listen time: 30m 37s
View from the Thoraxcenter: TCT 23 Late-breaking Science Preview

Joost Daemen, Nicolas M Van Mieghem

Watch time: 25m 48s

Broadcast

Intervention
TIO Mechanical Circulatory Support 2023

Nicolas M Van Mieghem, Holger Thiele, Giuseppe Tarantini, et al

ESC 23 Late-breaking Science Wrap Up

Nicolas M Van Mieghem, Joost Daemen,

Listen time: 47m 56s

Nicolas M Van Mieghem, Joost Daemen

Watch time: 1h 35m 42s (16 videos)
View from the Thoraxcenter: ESC 23 Late-breaking Science Preview

Joost Daemen, Nicolas M Van Mieghem,

Listen time: 28m 32s
View from the Thoraxcenter: ESC 23 Late-breaking Science Preview

Nicolas M Van Mieghem, Joost Daemen

Watch time: 28m 31s

Broadcast

Intervention
Transcatheter Interventions Online 2024 - Day Three

Nicolas M Van Mieghem, Kendra J Grubb, David Hildick-Smith, et al

Watch time: 3h

Broadcast

Intervention
Transcatheter Interventions Online 2024 - Day Two

Nicolas M Van Mieghem, Kendra J Grubb, David Hildick-Smith, et al

Watch time: 4h

Broadcast

Intervention
Transcatheter Interventions Online 2024 - Day One

Nicolas M Van Mieghem, Kendra J Grubb, David Hildick-Smith, et al

Watch time: 4h

Articles by Nicolas M Van Mieghem, Medical Director

Incidence and Pathology of Aortic Regurgitation

Lucas Uchoa de Assis, Giulio M Mondellini, Mark MP van den Dorpel, et al

Published:

Citation: Interventional Cardiology 2025;20:e07.

DOI:

https://doi.org/10.15420/icr.2024.37
Conduction Abnormalities after Transcatheter Aortic Valve Implantation: Incidence, Impact and Management Using CT Data Interpretation

Rutger-Jan Nuis, Mark van den Dorpel, Rik Adrichem, et al

Published:

Citation: Interventional Cardiology 2024;19:e12.

DOI:

https://doi.org/10.15420/icr.2024.11
Precision Medicine in Interventional Cardiology

Thijmen W Hokken, Joana M Ribeiro, Peter P De Jaegere, et al

Published:

Citation: Interventional Cardiology Review 2020;15:e03.

DOI:

https://doi.org/10.15420/icr.2019.23
Aortic Stenosis and Heart Failure: Disease Ascertainment and Statistical Considerations for Clinical Trials

Ernest Spitzer, Rebecca T Hahn, Philippe Pibarot, et al

Published:

Citation: Cardiac Failure Review 2019;5(2):99–105.

DOI:

https://doi.org/10.15420/cfr.2018.41.2
Coronary Calcified Lesions: Introduction to the Focused Issue

Nicolas M Van Mieghem,

Published:

Citation: Interventional Cardiology Review 2019;14(3):152–3.

DOI:

https://doi.org/10.15420/icr.2019.14.3.GE1
Large-bore Vascular Closure: New Devices and Techniques

Maarten P van Wiechen, Jurgen M Ligthart, Nicolas M Van Mieghem, et al

Published:

Citation: Interventional Cardiology Review 2019;14(1):17–21

DOI:

https://doi.org/10.15420/icr.2018.36.1
The Role of Automated 3D Echocardiography for Left Ventricular Ejection Fraction Assessment

Ernest Spitzer, Ben Ren, Felix Zijlstra, et al

Citation: Cardiac Failure Review 2017;3(2):97–101.

DOI:

https://doi.org/10.15420/cfr.2017:14.1
Need for Embolic Protection During Transcatheter Aortic Valve Implantation: An Interventionalist’s Perspective on Histopathology Findings

Herbert G Kroon, Nicolas M Van Mieghem,

Citation: Interventional Cardiology Review 2017;12(1):36–9

DOI:

https://doi.org/10.15420/icr.2016:30:2
Personal Experience with Bioresorbable Scaffolds in Bifurcations

Roberto Diletti, Nicolas M Van Mieghem,

Citation: Interventional Cardiology Review 2013;8(2):93-5

DOI:

https://doi.org/10.15420/icr.2013.8.2.93
Cardiovascular Clinical Trials in a Pandemic: Immediate Implications of Coronavirus Disease 2019

Ernest Spitzer, Ben Ren, Jasper J Brugts, et al

Published:

Citation: Cardiac Failure Review 2020;6:e09.

DOI:

https://doi.org/10.15420/cfr.2020.07
A42 - Pressure and Volume Unloading with Pulsatile Circulatory Support During High-risk Percutaneous Revascularisation

MB Bastos, JJ Schreuder, Joost Daemen, et al

Published:

Citation: Interventional Cardiology Review 2019;14(3 Suppl 1):A42.

DOI:

https://doi.org/10.15420/icr.2019.14.3.S1