Acute Coronary Syndromes
-
Acute coronary syndrome (ACS) is one of the most common health problems globally and a leading cause of death and signficiant morbidity in developed countries. It represents a clinical condition characterised by rapidly developing critical myocardial ischaemia. ACS encompasses three related but distinct clinical entities – unstable angina, non-ST-segment elevation MI (NSTEMI), and ST-segment elevation MI (STEMI).
Load moreAcute coronary syndrome (ACS) is one of the most common health problems globally and a leading cause of death and signficiant morbidity in developed countries. It represents a clinical condition characterised by rapidly developing critical myocardial ischaemia. ACS encompasses three related but distinct clinical entities – unstable angina, non-ST-segment elevation MI (NSTEMI), and ST-segment elevation MI (STEMI).
Acute coronary syndromes are characterised by vascular inflammation, subsequent endothelial dysfunction and platelet activation, followed by thrombus formation. Uncontrolled thrombosis can culminate in complete vascular occlusion and STEMI.
Key diagnostic procedures for detection of patients with ACS are ECG at rest and markers of myocardial necrosis. Optical coherence tomography can be used to assess patients with ACS and is useful because it can detect plaques at high risk of rupture and provide additional information about plaque composition, thrombi and collagen. Troponin T and troponin I are specific cardiac markers for myocardial injury and diagnosing the myocardial necrosis.
Management of ACS should encompass both acute and long-term strategies.
Load Less
Videos
-
29 August 2017
-
18 March 2017
-
13 March 2017
-
18 August 2016
Pages
-
Christopher N FloydEuropean Cardiology Review 2020;15:e08.DOI: https://doi.org/10.15420/ecr.2019.09
-
Tamara García Camarero, Jose M de la Torre HernandezEuropean Cardiology Review 2020;15:e07.DOI: https://doi.org/10.15420/ecr.2019.25.2
-
Mahmoud Abdelnabi, Abdallah Almaghraby, Yehia Saleh, et alEuropean Cardiology Review 2020;15:e06.DOI: https://doi.org/10.15420/ecr.2019.1.3
-
Anandita Agarwala, Michael D ShapiroEuropean Cardiology Review 2020;15:e05.DOI: https://doi.org/10.15420/ecr.2019.16
